多机构回顾性研究调查了701只狗的血液培养方案和测试阳性
Andrzej J Ogrodny1, Rinosh Mani2, Sarah M Schmid3,4
1Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI, United States.
Frontiers in veterinary science
|December 28, 2023
概括
狗的阳性尿液培养显著增加了阳性血液培养 (BC) 的可能性. 收集三个BC标本为正确结果提供了最好的机会,有助于诊断犬类感染.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 传染性疾病 传染性疾病
- 诊断微生物学 诊断微生物学
背景情况:
- 血培养 (BC) 阳性对于诊断狗的全身感染至关重要.
- 影响BC阳性的因素,包括样本采集协议和患者状况,需要进一步调查.
研究的目的:
- 评估样本采集时间和数量,原发性疾病和先前治疗对狗血培养阳性的影响.
- 评估尿液培养和血液培养结果在狗患者之间的一致性.
主要方法:
- 一项多机构的回顾性研究分析了2019年至2022年间701只狗的数据.
- 混合效应的逻辑回归模型被用来识别与血培养阳性相关的因素.
- 使用后勤回归来确定尿液和血液培养结果之间的关联.
主要成果:
- 具有阳性尿液培养的狗显著更有可能具有阳性血液培养 (OR:4.36).
- 收集三种血液培养样本产生了最高的阳性结果的概率,尽管在统计学上并不显著.
- 观察到抗微生物药物耐药性来自38.5%的具有阳性血液培养的狗的隔离物.
结论:
- 阳性尿液培养是狗潜在细菌病的强有力的指标.
- 优化血液培养采集协议,例如样本数量,可能会提高诊断产量.
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