孟加拉国人口中的脑静脉血栓:系统性审查
Redoy Ranjan1,2, Gie Ken-Dror1, Md Atikul Aziz3
1Biological Sciences, Royal Holloway University of London, London, GBR.
Cureus
|December 28, 2023
概括
脑静脉血栓 (CVT) 在孟加拉国女性中更为常见,影响她们的频率是男性的1.5倍,比男性早13年. 及时诊断和抗凝治疗导致良好的临床结果.
科学领域:
- 神经学 神经学
- 血管医学 血管医学
- 公共卫生 公共卫生
背景情况:
- 大脑静脉血栓塞 (CVT) 是孟加拉国中风的一个未被认可的原因.
- 关于孟加拉国人口中CVT患者的特定特征和结果的数据有限.
研究的目的:
- 对孟加拉国被诊断患有CVT的患者发表的数据进行全面审查.
- 分析该群体中发病年龄,性别分布,放射学发现和患者结果.
主要方法:
- 在2023年11月之前,系统地搜索电子数据库,查找孟加拉国关于CVT的所有已发表的研究.
- 包括13项研究 (2项观察性,11项病例报告),涉及102名CVT患者.
- 对人口统计,放射学和治疗数据的审查.
主要成果:
- 女性占CVT患者的59.8%,明显高于男性 (40.2%).
- 总体平均年龄为36.6±6.8岁;男性年龄明显大 (45.4±12.3) 比女性年龄大 (32.4±8.3).
- 最常见的受影响部位是上部斜侧鼻和横侧鼻;里瓦洛克萨班是一种常见的长期抗凝剂.
结论:
- 在孟加拉国,CVT不成比例地影响女性,她们的诊断率比男性高1.5倍,比男性早13年.
- 早期诊断和抗凝药,包括初始的低分子量肝素,其次是里瓦洛克萨班,与有利的临床结果和重新道化有关.
- 建议进行进一步的研究,以评估口服抗凝剂的长期结果,安全性和有效性,以及再通道化和复发率.
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