果在不同pH值下作为抗菌剂的有效性:一个试管测试研究
Prasanna Chandraseharan1, S Nagarajan Mp Sockalingam2, Zaleha Shafiei3
1Department of Family Oral Health, Faculty of Dentistry, The National University of Malaysia (UKM), Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Malaysia, https://orcid.org/0000-0002-1387-5848.
The journal of contemporary dental practice
|December 28, 2023
概括
果 (ACV) 对常见的牙科细菌,如Enterococcus faecalis和Streptococcus mutans,表现出抗菌作用. 这种天然消毒剂在牙纸治疗中显示出作为二酸盐的安全替代品的潜力.
科学领域:
- 微生物学 微生物学
- 生物化学 生物化学
- 牙科科学 牙科科学
背景情况:
- 牙损伤和肉感染通常是由细菌引起的,例如Enterococcus faecalis,Streptococcus mutans和Lactobacillus casei.
- 低酸 (NaOCl) 是一种常见的牙科消毒剂,但它可能会引起不良反应.
- 果 (ACV) 是一种天然产品,具有潜在的抗菌特性.
研究的目的:
- 为了评估5%的果 (ACV) 对Enterococcus faecalis,Streptococcus mutans和Lactobacillus casei.的抗菌活性.
- 为了比较ACV与酸盐 (NaOCl) 和酸 (AA) 的疗效.
- 用传输电子显微镜 (TEM) 观察用ACV治疗的细菌的结构变化.
主要方法:
- 使用微稀释方法来确定最小抑制度 (MIC) 和最小杀菌度 (MBC).
- 5.25%的NaOCl作为阳性对照.
- 用ACV治疗的细菌使用TEM检查了形态变化.
主要成果:
- 发现ACV的MIC为S. mutans和E. faecalis的0.625%,L. casei的1.25% (两倍稀释).
- 与NaOCl (p > 0.05) 相比,ACV在抗菌活性上没有显著差异.
- 在MIC值下,TEM揭示了所有三种细菌细胞壁和细胞质膜的破坏.
结论:
- 果对E. faecalis,S. mutans和L. casei具有显著的抗菌活性.
- 在牙纸治疗中,ACV可以被视为一种安全有效的替代消毒剂,特别是在儿科病例和深层病管理中.
- 这些发现表明,酸盐可以帮助避免与传统化学消毒剂相关的不良反应.
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