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长期牙周炎中的唾液氨酶和真菌素:治疗前/后

Ebenezer Mani¹, Irudhaya Nirmala¹, P Sivasankar²

¹Department of Periodontics, Adhiparasakthi Dental College, Melmaruvathur, Tamil Nadu, India.

The journal of contemporary dental practice

|December 28, 2023

概括

唾液氨酶和粘素显示出作为诊断牙周病和监测治疗有效性的非侵入性生物标志物的潜力. 治疗后牙周炎患者的较高水平下降,与改善的临床结果相关.

科学领域:

生物化学生化学
牙周病学牙周病学
生物标志物发现发现

背景情况:

牙周病的诊断依赖于临床参数.
对于早期检测和监测,需要使用非侵入性生物标志物.

研究的目的:

评估唾液氨酶和粘素作为牙周病进展的生化标志物.
为了将唾液生物标志物水平与牙周病的严重程度和治疗结果相关联.

主要方法:

40名参与者 (20名对照组,20名牙周炎) 进行了临床参数和唾液氨基酸/乳素水平的评估.
在I期牙周治疗前和后分析了样本.
统计分析包括t测试和相关性分析.

主要成果:

牙周炎患者的唾液氨酶和粘素水平在基线较高,临床参数较差.
第一阶段治疗减少了唾液生物标志物,改善了临床结果.
在临床参数和唾液生物标志物之间观察到显著的正相关性.

结论:

唾液氨酶和粘素是诊断活跃牙周病的有希望的生物标志物.
这些生物标志物有助于评估治疗疗效和计划个性化护理.
需要进一步的研究才能充分确定它们的临床效用.

关键词:

氨基酶是一种氨基酶.慢性牙周炎慢性牙周炎临床依恋水平临床依恋水平粘素口腔卫生指数-简化.

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