一个家庭遗传研究青年的强迫症
Daniel A Geller1,2, Mia Grossman1
1Massachusetts General Hospital, Boston, USA.
Journal of attention disorders
|December 28, 2023
概括
儿科强迫症 (OCD) 显示出更高的家族传播率. 强迫症儿童的一级亲属有强迫症,症和多动症的风险增加.
科学领域:
- 遗传学 是一个遗传学.
- 精神病学是一个精神病学.
- 儿科健康 儿科健康
背景情况:
- 强迫症 (OCD) 是一种令人虚弱的心理健康状况.
- 了解家族风险对于儿童群体的早期干预至关重要.
研究的目的:
- 评估强迫症 (OCD) 和相关并发症的家族风险.
- 评估儿科发病的强迫症患者的第一级亲属.
主要方法:
- 家庭遗传研究涉及儿科强迫症试验者,兄弟姐妹,父母和对照.
- 使用结构化诊断访谈和临床证据直接进行精神病学评估.
主要成果:
- 在试验者中增加了焦虑,情绪,破坏性行为和动障碍的比例.
- 一级亲属显示强迫症 (26%),慢性/图雷特障碍 (9%) 和ADHD (21%) 的患病率增加.
结论:
- 强迫症和并发症的家族传播在儿科发病例中明显高于成人发病的强迫症.
- 早期出现的强迫症具有强烈的遗传成分,对家庭查有影响.
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