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Updated: Jul 6, 2025

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
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针对性质谱分析结肠直肠癌样本体质突变,使用差异离子运动

Zhaoguan Wu1,2, Éric Bonneil1, Michael Belford3

  • 1Institute for Research in Immunology and Cancer (IRIC) Université de Montréal, Montréal H3T 1J4, Canada.

Journal of proteome research
|December 28, 2023
PubMed
概括

在结直肠癌 (CRC) 中检测K-Ras和B-Raf突变对于有效的抗EGFR治疗至关重要. 这项研究使用并行反应监测 (PRM) 和高场不对称波形离子流动性 (FAIMS) 质谱学来提高突变检测灵敏度.

关键词:
这就是BRAF.克拉斯 (Kras) 是一个国家.结肠直肠癌突变变异的发生高场不对称波形离子移动性 (FAIMS)质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量平行反应监测 (PRM) 是指对反应进行平行监测.

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