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Updated: Jul 6, 2025

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SARS-CoV-2核体蛋白质的失序的N端尾部与RNA形成了一个动态复合体

Jasmine Cubuk1,2, Jhullian J Alston1,2, J Jeremías Incicco1,2

  • 1Department of Biochemistry and Molecular Biophysics, Washington University in St Louis, 660 St Euclid Ave, 63110 Saint Louis, MO, USA.

Nucleic acids research
|December 28, 2023
PubMed
概括

在SARS-CoV-2核囊蛋白的失序N-终端域显著增强RNA结合亲和力. 奥米克龙变异突变会影响这些相互作用,这表明N端域在病毒基因组凝聚中的功能作用.

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