仅抵抗和并发运动诱导类似的肌纤维细胞蛋白质合成率和相关的分子反应在训练前和训练后适度活跃的男性
Matthew J Lee1, Nikeisha J Caruana1,2, Nicholas J Saner1
1Institute for Health and Sport, Victoria University, Melbourne, Victoria, Australia.
概括
同时炼,结合有氧和抵抗训练,不会阻碍肌肉生长 (肌纤维蛋白合成). 然而,随着时间的推移,训练适应可能会减少运动诱导的分子反应.
科学领域:
- 运动生理学 运动生理学
- 分子生物学分子生物学
- 运动科学 运动科学 运动科学
背景情况:
- 有氧和阻力运动 (RE) 引起了不同的分子信号通路.
- 一个普遍的假设表明,这些途径可能是对抗性的,当与有氧运动相结合时,可能会损害对RE的合成反应.
研究的目的:
- 研究并发运动对肌纤维细胞蛋白质合成 (MyoPS) 和分子反应的影响.
- 检查10周的培训干预对这些反应的影响.
- 为了确定与运动同时进行的运动是否会损害对RE的合成反应.
主要方法:
- 适度活跃的男性接受了为期10周的仅抗力运动 (RE),RE加高强度间歇运动 (RE+HIIE) 或HIIE+RE.
- 使用二氧化 (D2O) 测量了MyoPS率.
- 肌肉活检分析了蛋白质合成和肌肉糖原的分子标记物.
主要成果:
- 在所有组中,MyoPS率是可比的,不论行使顺序如何.
- 同时炼并没有对RE的合成反应产生负面影响.
- 训练适应导致MyoPS和特定基因表达 (PGC-1ɑ,MuRF1) 的运动诱导变化减弱.
结论:
- 同时炼,无论是以何种顺序,都不会损害对抗力炼的合成反应.
- 训练状态会影响运动后的分子信号传递,一些反应在10周后会减弱.
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