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在用于诊断肌肉侵入性膀癌的膀成像报告和数据系统中规范化明显扩散系数的意义

Peikun Liu¹, Lingkai Cai¹, Ruixi Yu¹

¹Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Journal of magnetic resonance imaging : JMRI

|December 28, 2023

概括

当与膀成像报告和数据系统 (VI-RADS) 结合使用时,正常化明显扩散系数 (NADC) 改善了膀癌症的诊断. 这种组合增强了肌肉侵入性膀癌 (MIBC) 的检测能力.

科学领域:

放射学放射学是一门学科.
在瘤学瘤学.
医疗成像医学成像

背景情况:

膀成像报告和数据系统 (VI-RADS) 用于通过多参数MRI (mpMRI) 来评估膀癌症.
然而,VI-RADS对肌肉侵入性膀癌 (MIBC) 的诊断性能目前还不够理想.

研究的目的:

探索正常化表面扩散系数 (NADC) 与膀癌临床病理特征之间的关系.
评估是否将NADC纳入VI-RADS可以改善MIBC诊断.

主要方法:

对275名病理确诊的膀癌患者 (101个MIBC,174个NMIBC) 的回顾性分析,使用3-T mpMRI.
使用后勤回归来开发模型 (VI-RADS, VN, 图像, LN, 完整) 来区分MIBC和NMIBC.
接收器操作特征 (ROC) 曲线和DeLong的测试用于模型评估.

主要成果:

较低的NADC值与较大的瘤大小 (≥3厘米),MIBC,高组织学等级,淋巴结转移和淋巴血管入侵有显著关联.
与单独使用VI-RADS模型相比,采用NADC (VN,图像,完整) 的模型显示诊断准确率 (AUC) 显著更高.
结合VI-RADS评分和NADC的VN模型显示了与图像模型相比的性能.

结论:

NADC提供了有关膀癌攻击性的宝贵信息.
将NADC与VI-RADS集成显著提高了肌肉侵入性膀癌的诊断能力.

关键词:

膀成像-报告和数据系统显而易见的扩散系数值值.膀癌:膀癌是一种癌症.诊断性表现的诊断性表现是什么

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