对于平均风险和高风险个体的结肠直肠癌查指南:系统性审查
Caroline Tanadi1, Kevin Tandarto2, Maureen Miracle Stella1
11Medical Profession Study Program, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.
概括
对于平均风险的个体,建议在45-75岁之间进行结肠直肠癌查. 高危人群,如有家族病史的人群,应在40岁开始查.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 预防医学 预防医学
背景情况:
- 结肠直肠癌 (CRC) 仍然是一个重大的全球健康问题.
- 查指南各不相同,需要为临床实践提供整合的概述.
- 通过查及早检测可以大大改善患者的治疗结果和生存率.
研究的目的:
- 系统地审查和综合目前关于结直肠癌查的国际指南.
- 为了对平均风险和高风险人群的建议进行比较.
- 确定关于查方式和间隔的共识.
主要方法:
- 在主要数据库 (EBSCOhost,JSTOR,PubMed,ProQuest,SAGE,ScienceDirect) 中进行了全面的文献搜索.
- 包括2012年1月至2022年8月期间发布的指导方针,共识建议和立场声明.
- 总共有18个相关的指导方针被确定和分析.
主要成果:
- 大多数指导方针建议对45至75岁的平均风险人群进行结直肠癌查.
- 对于高风险个体的查建议有所不同,建议较早开始 (40岁) 对于具有阳性家族病史或晚期息肉的人.
- 通常推的查方法包括结肠镜检查,便免疫化学测试 (FIT) 和CT结肠镜检查 (CTC),为每个风险组提供特定的间隔.
结论:
- 平均风险人群应在45-75岁之间开始进行结肠直肠癌查.
- 高风险人群,特别是那些有CRC家族病史的人,应该在40岁时更早开始查.
- 推的查间隔和方法 (结肠镜检查,FIT,CTC) 根据个体风险因素而异.
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