移植期间的酸参数与移植中移植功能障碍类型之间的关联
Teodor Căluşi1, Bogdan Sorohan2,3, Alexandru Iordache4
11Intensive Care Unit, Department 2, Fundeni Clinical Institute, Fundeni Street No 258, District 2, Zip Code 022328, Bucharest, Romania.
概括
在移植患者中,外科手术期间发生的代谢酸与缓慢的移植功能 (SGF) 和延迟的移植功能 (DGF) 有关. 监测酸平衡可能有助于预测这些移植功能障碍类型.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 移植手术 移植手术
- 关键护理医学 关键护理医学
背景情况:
- 外科手术期间的酸干扰可能表明移植 (KT) 后的移植功能障碍.
- 有限的数据存在于KT接受者间的术后酸状态和移植功能障碍 (慢移植功能[SGF]或延迟移植功能[DGF]) 之间的关联.
研究的目的:
- 为了确定SGF和DGF在KT受益者的发病率.
- 调查术前酸参数与SGF或DGF的发展之间的关联.
主要方法:
- 54名成年 KT 接受者的前性队列研究.
- 根据血清肌水平和透析需求,移植功能被分类为即时 (IGF),SGF或DGF.
- 对外科手术期间的酸参数进行分析,包括pH值,过量 (BE) 和血清二碳酸盐 (HCO3-).
主要成果:
- SGF的发病率为13%,而DGF的发病率为11.1%.
- 与IGF相比,SGF和DGF与较低的手术内pH值,较低的手术前和手术内基过量以及较低的血清二碳酸盐显著相关.
- 在SGF和DGF组之间没有观察到术前酸参数的显著差异.
结论:
- 外科手术期间的酸参数与移植患者的移植功能障碍类型 (SGF/DGF) 有关.
- 外科手术期间的代谢酸症可以作为SGF或DGF发生的预测因素,强调酸监测的重要性.
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