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在COVID-19患者中,染色失调和对比度敏感度的变化

Aditi Sharma¹, Aditya Singh¹, Yashik Bansal²

¹Department of Ophthalmology, VCSG Government Institute of Medical Science and Research, Srinagar, Uttarakhand, India.

Indian journal of ophthalmology

|December 28, 2023

概括

COVID-19患者的色调歧视 (总估计得分) 显著改变,这是一种类似于嗅觉丧失的眼睛征兆. 对比度灵敏度在很大程度上不受感染的影响.

科学领域:

眼科医生眼科眼科
传染性疾病传染性疾病
神经科学是一个神经科学.

背景情况:

COVID-19可能会导致神经和感官功能障碍.
越来越多地报道了COVID-19的眼部表现.
了解COVID-19的视觉影响对于患者管理至关重要.

研究的目的:

评估COVID-19患者对比度敏感性 (CS) 和色调歧视 (总估计得分,TES) 的变化.
为了将视觉功能变化与COVID-19感染状态相关联.

主要方法:

一项前性病例控制研究比较了COVID-19患者与RT-PCR负控.
移动应用程序"智能光学"和Farnsworth-Munsell 100色彩测试评估了CS和TES.
排除标准确保了预先存在的视觉条件的最小混;多变量回归分析了年龄/性别影响.

主要成果:

与对照组相比,在COVID-19患者中观察到TES的显著恶化 (p <0.001).
突破性感染也导致TES显著下降 (p = 0.04).
通过S介导的缺陷比M-L缺陷更为普遍;CS基本没有变化.

结论:

COVID-19 感染显著改变色彩歧视 (色差),眼睛与厌氧相关.
对比度灵敏度在COVID-19患者中显示最小的变化.
在COVID-19患者中,应考虑视觉功能变化,特别是色差.

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