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相关概念视频

Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

114
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
114

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相关实验视频

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A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
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在认知衰退的老年成年人中休息状态功能连接和认知表现:数据驱动的多变量模式分析.

Hesun Erin Kim1, Jae-Jin Kim2, Jeong-Ho Seok2

  • 1Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.

Comprehensive psychiatry
|December 28, 2023
PubMed
概括

这项研究表明,小脑和小岛连接模式对于老年人的整体认知能力下降至关重要. 它还确定了一个独立的基本认知功能的受损模式,独立于衰退的严重程度.

关键词:
衰老的衰老 衰老的衰老认知能力下降 认知能力下降数据驱动的科学数据驱动的科学功能神经成像功能神经成像神经心理测试 神经心理测试

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科学领域:

  • 神经科学是一个神经科学.
  • 认知科学 认知科学
  • 衰老研究研究 衰老研究

背景情况:

  • 认知障碍存在于个体变化的频谱中,但这些领域通常被孤立地研究.
  • 了解不同认知领域及其神经支在衰老中的相互作用至关重要.

研究的目的:

  • 调查与年龄相关的认知能力和静止状态功能连接 (rsFC) 的个体变化.
  • 在认知能力下降的老年人中识别认知性能和相关的神经连接的数据驱动模式.

主要方法:

  • 在62名老年门诊患者的认知数据上利用主要组件分析 (PCA) 来识别认知表现模式.
  • 应用全大脑连接组多变量模式分析 (MVPA) 到神经成像数据,以将神经区域与认知特征联系起来.

主要成果:

  • 第一个主要组成部分 (PC1) 表示所有认知领域的总体下降.
  • 小脑和脑岛与主要大脑网络的休息状态功能连接 (rsFC) 与PC1.0相反相关.
  • 第二个组件 (PC2) 揭示了基本认知功能中的补偿关系,与极和皮层连接相关.

结论:

  • 小脑和小岛连接模式是老化过程中一般认知能力下降的关键指标.
  • 鉴定出一种明显的基本认知功能受损模式,独立于整体衰退的严重程度.