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Updated: Sep 1, 2026

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对PAH4诱导的肝毒性和大鼠模型中剂量反应评估的新见解

Miao Yang1, Yuxuan Lu1, Weifeng Mao2

  • 1Department of Nutrition and Food Hygiene, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China; Hubei Key Laboratory of Food Nutrition and Safety, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China; Ministry of Education Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Chemosphere
|December 28, 2023
PubMed
概括

多环芳香碳化合物4 (PAH4) 暴露会导致大鼠的肝毒性和脂质代谢障碍. 本研究建立了PAH4的剂量反应关系,有助于对这些环境污染物的风险评估.

关键词:
基准剂量的基准剂量剂量反应评估剂量反应评估肝毒性 肝毒性 肝毒性代谢学 代谢学 代谢学单基化PAH代谢物 (OH-PAH) 的代谢物.多环芳香碳化合物 多环芳香碳化合物

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