患有IBD的人在睡眠架构评估期间有更多的微刺激证据
Jessica K Salwen-Deremer1,2, Matthew J Reid3, Sarah J Westvold2,4
1Department of Psychiatry, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA jessica.k.salwen-deremer@hitchcock.org.
BMJ open gastroenterology
|December 28, 2023
概括
与健康人相比,炎症性肠病 (IBD) 患者表现出更多的睡眠障碍,特别是微刺激. 客观的睡眠评估对于理解IBD中的睡眠障碍至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 睡眠医学 睡眠医学
- 精神病学是一个精神病学.
背景情况:
- 睡眠不足在炎症性肠病 (IBD) 中普遍存在,并与更糟糕的结果有关.
- 现有的研究往往依赖于主观的睡眠报告或可疑有效性的单一夜间客观测量.
- 了解IBD的客观睡眠结构是必不可少的.
研究的目的:
- 客观地评估IBD患者的睡眠架构,使用多夜电脑图 (EEG).
- 为了比较IBD患者和健康对照者的睡眠模式.
- 探索睡眠障碍,精神病并发症和IBD中的疾病活动之间的关联.
主要方法:
- 从达特斯 - 希奇考克医疗中心招募了IBD和健康对照的参与者.
- 为了评估睡眠架构,利用了三晚的家庭电脑图 (EEG) 监测.
- 根据美国睡眠医学学会指导方针得分的睡眠数据.
主要成果:
- 患有IBD的参与者 (n=15) 显示出比健康对照组 (n=8) 更多的微刺激.
- IBD患者报告失眠,焦虑和抑郁的比率更高.
- 在IBD中,微刺激与更低的失眠和更高的抑郁症得分有关;睡眠效率显示出失眠患者的减少趋势.
结论:
- 多夜EEG提供了比以前的方法更强大的评估IBD的睡眠架构.
- 增加的微刺激是IBD患者的客观睡眠障碍.
- 未来的研究应该采用严格的多夜睡眠评估,并探索IBD睡眠障碍中的认知/行为因素.
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