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Biological Effects of Radiation02:59

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All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
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血液中氧化过程的强度和血液中亡的水平 放射学家/X射线技术人员暴露于少量电离辐射的淋巴细胞/X射线技术人员.

O A Glavin1, E A Domina1, V S Ivankova2

  • 1R. E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of the National Academy of Sciences of Ukraine, 45 Vasylkivska Str., Kyiv, 03022, Ukraine.

Problemy radiatsiinoi medytsyny ta radiobiolohii
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概括

放射科医生暴露于低剂量的电离辐射显示氧化应激增加和淋巴细胞亡减少. 氧化还原平衡的这种转变可能会增加这些细胞中遗传损伤的风险.

关键词:
灭症 (apoptosis) 是一种死亡的过程.氧化代谢的指标.电离辐射辐射的电离辐射.淋巴细胞 淋巴细胞周围血液 周围血液放射科医生/X射线技术专家

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科学领域:

  • 生物医学科学 生物医学科学
  • 职业健康 职业健康 职业健康 职业健康
  • 辐射生物学 辐射生物学

背景情况:

  • 对低剂量电离辐射的职业暴露对于放射科医生和X射线技术人员来说是常见的.
  • 了解这种暴露对细胞健康的影响对于工人安全至关重要.

研究的目的:

  • 研究暴露于电离辐射的专业人员的外周血液氧化还原状态和淋巴细胞亡的变化.
  • 评估医疗成像专业人员与职业辐射暴露相关的潜在健康风险.

主要方法:

  • 分析了45名放射科医生/X射线技术人员和52名健康对照者的血液样本.
  • 测量马隆迪甲基,硫基,催化酶活性,超氧化离子激素生成和淋巴细胞亡.

主要成果:

  • 专业人士显示,马隆迪化物增加了1.49倍,硫基减少了1.67倍.
  • 超氧化离子基的产生增加了1.56倍,这表明向亲氧化过程的转变.
  • 在暴露组中,外周血液淋巴细胞亡减少了1.35倍,亡,自由基化合物和辐射暴露之间存在相关性.

结论:

  • 低剂量的电离辐射暴露会改变血液的氧化还原平衡,这表明放射科医生有潜在的氧化应激.
  • 在暴露的专业人员中减少的淋巴细胞亡可能会构成积累遗传损伤的风险.