开发基于水凝的标准和幻影,用于深度非线性成像
Fizza Haseeb1, Konstantinos N Bourdakos2, Ewan Forsyth1
1University of Edinburgh, School of Chemistry, Edinburgh, United Kingdom.
Journal of biomedical optics
|December 29, 2023
概括
新的柔性水凝幻象使深层组织成像验证. 这些具有嵌入式标记的多层光学标准允许对先进的成像技术进行精确的深度评估.
科学领域:
- 生物医学光学 生物医学光学
- 材料科学 材料科学 材料科学
- 医疗成像医学成像
背景情况:
- 深层组织成像正在通过新的光学技术迅速发展.
- 可靠的标准和幻影对于验证和优化这些先进的成像技术至关重要.
研究的目的:
- 设计和创建灵活的,多层水凝基础的光学标准.
- 评估用于深层组织透的先进光学成像技术.
主要方法:
- 使用阿加和聚烯胺制造强大的双网水凝矩阵.
- 创建具有嵌入模式特定标记的多层结构 (最多七层).
- 测试各种成像方式的幻影的稳定性和实用性.
主要成果:
- 水凝标准在确定光显微镜的轴向缩放因子方面表现出有效性.
- 对一光子和两光子激发光成像,第二波生成和连贯的反斯托克斯拉曼散射进行了深度评估.
- 幻影实现了高达1550微米的成像深度,并长时间保持稳定.
结论:
- 开发的幻影是坚固的,灵活的,并包含光学标记器用于深度标准化.
- 这些标准非常适合验证各种深层组织成像模式.
- 该技术促进了先进光学成像的优化和可靠应用.
相关概念视频
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Deconvolution, also known as inverse filtering, is the process of extracting the impulse response from known input and output signals. This technique is vital in scenarios where the system's characteristics are unknown, and they must be inferred from the observable signals.
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