患有渐进性超核性麻的患者的主观认知投诉
Jun Seok Lee1,2, Jong Hyeon Ahn1,2, Jong Mok Ha1,2
1Department of Neurology, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Frontiers in neurology
|December 29, 2023
概括
主观认知投诉 (SCC) 在逐渐超核性麻 (PSP) 中很常见. 在患有轻度认知障碍的PSP患者中,SCC表明认知功能恶化,需要医生评估及时诊断和管理.
科学领域:
- 神经学 神经学
- 神经心理学 神经心理学
- 认知科学 认知科学
背景情况:
- 主观认知投诉 (SCC) 是自我报告的认知下降,在像帕金森病这样的神经退行性疾病中很普遍.
- 进展性上核性麻 (PSP) 中SCC的患病率和临床特征尚未得到充分研究.
- 了解PSP中的SCC对于早期发现和管理认知障碍至关重要.
研究的目的:
- 在没有痴呆症的PSP患者中调查SCC的患病率和临床特征.
- 为了比较PSP患者与没有SCC之间的认知功能和临床特征.
- 确定SCC是否与PSP的特定认知缺陷有关.
主要方法:
- 招募了83名没有痴呆症的PSP患者.
- 通过半结构面试评估SCC.
- 进行了全面的神经心理测试,并根据SCC存在和认知状态 (正常认知[NC]与轻度认知障碍[MCI]) 进行了临床特征的比较.
主要成果:
- 43.4%的PSP患者报告SCC.
- 在NC (37.5%) 和MCI (44.8%) PSP组中,SCC的患病率相似.
- 与没有SCC (MCI-SCC) 的MCI患者相比,患有MCI和SCC (MCI+SCC) 的PSP患者在注意力,语言,视觉记忆和前额执行功能方面表现明显差.
结论:
- SCC经常被PSP患者报告,特别是那些患有MCI的人.
- 在患有MCI的PSP患者中,SCC与多个认知领域的表现较差有关.
- 医生应评估PSP患者的SCC,以促进及时诊断和管理认知衰退.
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