在CHU穆罕默德六世医院COVID-19之前和期间,多药耐药细菌的微生物学概况
Hind Bennani1,2, Morad Guennouni3,4, Assia El Ouarradi1,2
1Laboratory of Microbiology, Mohamed VI University Hospital Center, Marrakesh, Morocco.
Iranian journal of microbiology
|December 29, 2023
概括
随着COVID-19大流行,多抗药性细菌 (MDRB) 的发生率显著增加,特别是在血液培养和其他关键样本中. 这表明,大流行并没有减缓抗菌素耐药性的进展.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- 随着COVID-19大流行,全球卫生系统受到压力,临床实践发生了变化.
- 抗菌素耐药性 (AMR) 是一个日益增长的全球健康威胁.
- 疫情对抗菌素耐药性进展的影响需要紧急调查.
研究的目的:
- 评估COVID-19大流行对抗菌素耐药率的影响.
- 为了比较大流行之前和期间的AMR趋势.
主要方法:
- 采用了横截面研究设计.
- 抗菌素耐药性的数据是从马拉喀什的一所大学医院收集的.
- 数据涵盖了两个时期:大流行前 (2019年3月至2020年3月) 和大流行期间 (2020年3月至2021年3月).
主要成果:
- 观察到多药耐药细菌 (MDRB) 的显著增加,从27.38%上升到35.87% (p<0.001).
- 在血液培养,脑脊髓液,导管和样本中注意到增加.
- 特定的耐药菌株,如扩展光谱β-乳糖酶生成的Enterobacteriaceae,耐卡巴胺的Enterobacteriaceae和耐甲林的*金黄色葡萄球菌也上升了.
结论:
- COVID-19大流行与MDRB的显著增加有关.
- 这些发现表明,大流行并没有阻止抗菌素耐药性的进展.
- 持续的监测和干预策略对于在卫生危机期间对抗AMR的上升至关重要.
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