mitra 门手术对心室节律失常的作用在 mitra 门缩患者中:五年后续研究
E G Malev1, M Yu Omelchenko2, S V Reeva3
1St.-Petersburg State Pediatric Medical University, Saint Petersburg; Almazov National Medical Research Center, St.-Petersburg.
Kardiologiia
|December 29, 2023
概括
对缩和严重吐的 mitra 门手术减少了心室心律不整. 手术后的左心室改造和膜变化是持续性心律失常的关键危险因素.
科学领域:
- 心脏病学 心脏病学
- 心脏外科手术 心脏外科手术
- 电力生理学 电力生理学
背景情况:
- 由于 mitra (MV) 脱落,严重的 mitra 反 (MR) 可能导致心室心律失常 (VA).
- 手术干预旨在纠正MR并可能减轻心律失常风险.
研究的目的:
- 评估MV维修或更换对VA发病率的影响.
- 确定在 MV 脱落和严重MR患者手术后持续VA的预测因子.
主要方法:
- 对30名因严重MR而接受MV手术的患者进行前性观察性研究.
- 术前和术后的胸前心电回声和霍尔特监测.
- 切除的MV组织的组织病理学分析.
主要成果:
- 手术后观察到VA的显著下降,特别是心室性心力衰竭.
- 手术后的VA与左心室 (LV) 改造 (EDV,LVEF) 和MV神性变性相关.
- 增加的LV终端-透缩体积,LVEF<50%,和myxomatous MV退化是持续的VA的危险因素.
结论:
- MV手术有效地减少恶性VA在患者的MV缩和严重的MR.
- LV重塑和MV体变化的程度是影响术后VA持久性的关键因素.
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