患有非酒精性脂肪性肝病的患病率和预后价值,患者住院治疗失偿性慢性心力衰竭
I A Misan1, O S Arisheva2, I V Garmash2
1Patrice Lumumba Russian University of People's Friendship.
Kardiologiia
|December 29, 2023
概括
非酒精性脂肪性肝病 (NAFLD) 影响了近三分之一的无补偿慢性心力衰竭 (DCHF) 患者. 严重的NAFLD (S3) 与更糟糕的临床结果有关,包括死亡率和再入院.
科学领域:
- 心脏病学 心脏病学
- 肝病学 肝病学是一种肝病学.
- 内部医学 内部医学
背景情况:
- 非酒精性脂肪性肝病 (NAFLD) 越来越多地被认为是心血管疾病的并发症.
- 退补偿性慢性心力衰竭 (DCHF) 患者经常出现多种并发症,这些疾病可能会影响结果.
研究的目的:
- 调查DCHF患者中NAFLD的患病率.
- 确定NAFLD与该患者群体的临床结果之间的关联.
主要方法:
- 分析了338名NYHA III-IV类DCHF患者的队列.
- 诊断NAFLD是基于2021年的指导方针,通过暂时弹性度计 (CAP值) 确定肥胖症的阶段.
- 使用多变量回归和卡普兰-梅尔分析来评估预测因素和结果.
主要成果:
- 在28.9%的DCHF患者中诊断出NAFLD.
- 对NAFLD的独立预测因素包括静脉血压≥130 mmHg,2型糖尿病 (T2DM) 和腰围>111厘米.
- 严重的肥胖症 (CAP ≥331dB/m,S3) 与更糟糕的两年预后 (综合不良结果) 相关.
结论:
- 在近三分之一的DCHF患者中,NAFLD是普遍存在的.
- 动脉高血压,T2DM和腹部肥胖与较高的NAFLD风险有关.
- 严重的肝硬化症 (S3) 独立预测DCHF患者的不良临床结果.
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