Hsp 抑制剂通过调节 ERK/MAPK 信号通路对腺癌人类气膜基底上皮细胞具有影响力

Servet Tunoğlu1, Lütfi Tutar2, Mehmet Gümüş3

  • 1Department of Molecular Medicine, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey.

Chemistry & biodiversity
|December 29, 2023
PubMed
概括

通过向ERK-MAPK通路和热冲击蛋白90 (HSP90) 的作用,新型的围胺-皮拉化合物抑制了癌细胞的生存. 这些化合物显示出作为非小细胞肺癌 (NSCLC) 的抗癌药物具有前途.

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