通过皮肤的喉肉毒素注射的止痛:一个随机交叉试验
Richard Heyes1, Charles H Adler2, Claire Yee3
1Department of Otorhinolaryngology-Head and Neck Surgery, Mayo Clinic Arizona, Phoenix, Arizona, U.S.A.
The Laryngoscope
|December 29, 2023
概括
性失声症 (SD) 喉注射期间的疼痛与局部麻醉,振动棒或没有疼痛缓解时的疼痛相似. 患者更喜欢振动棒或没有麻醉而不是利多卡因,这表明个性化疼痛管理是关键.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经学 神经学
- 疼痛管理 疼痛管理
背景情况:
- 喉注射,特别是对于性失声症 (SD),可能是痛苦的.
- 在这些室内手术过程中改善患者体验至关重要.
- 目前文献缺乏关于清醒时进行喉注射的有效止痛方法的数据.
研究的目的:
- 评估局部麻醉剂和振动仪器在通过宫注射肉毒素时减轻疼痛的疗效.
- 为了比较患者报告的三种不同的止痛技术的疼痛水平.
- 为了确定患者在SD的喉注射期间对疼痛管理的偏好.
主要方法:
- 进行了一项未盲目的,前性随机对照试验,采用交叉设计.
- 32名附加体SD患者接受了通过皮肤注射肉毒素.
- 治疗包括无麻醉,局部麻醉 (2%利多卡因) 和振动仪器,随机顺序和患者偏好评估.
主要成果:
- 在三种止痛技术之间没有发现统计学上显著的疼痛差异 (p=0.38).
- 振动棒是最喜欢的技术 (44%),其次是利多卡因 (37%) 和无麻醉 (19%).
- 总共有63%的患者更喜欢振动棒或没有麻醉,而不是利多卡因.
结论:
- 在局部麻醉,振动仪器之间没有明显的疼痛感知差异,在喉肉毒素注射期间没有止痛作用.
- 超过一半的患者更喜欢不涉及利多卡因的技术,强调需要个性化疼痛管理.
- 建议对通过皮肤进行喉注射进行个性化止痛策略,以增强患者的体验.
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