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Updated: Jul 6, 2025

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
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Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells

Published on: February 21, 2018

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由C/EBPβ诱导的淋巴细胞转化为骨髓细胞的转化模拟了颗粒细胞-单细胞原生体生物学

Linh Thuy Nguyen1, Karin Zimmermann2, Elisabeth Kowenz-Leutz2

  • 1Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Roessle-Str. 10, Berlin, Germany; Berlin School of Integrative Oncology (BSIO), Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Stem cell reports
|December 29, 2023
PubMed
概括

CCAAT/增强酶结合蛋白β (C/EBPβ) 驱动B细胞转分成粒细胞-巨细胞原始细胞 (GMPBTs) 的过程. 这种可扩展的系统模拟了GMP生物学,减少了动物试验.

关键词:
这就是3R原则.在C/EBP中,它是最重要的.良好的生理惯例 (GMP) 是一个好方法.细胞的命运 细胞的命运颗粒细胞 - 巨细胞原始体血液形成 血液形成这种白血病是白血病.骨髓形成 (myelopoiesis) 是一种形成骨髓的过程.通过转差异化转化.

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