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Updated: Jul 6, 2025

Identification of Protein Complexes in Escherichia coli using Sequential Peptide Affinity Purification in Combination with Tandem Mass Spectrometry
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通过微珠辅助毛细血管电泳 (MACE) 有效地分离生物活性-ssDNA合体

Muneyuki Matsuo1, Koji Wakui2, Yuuki Inami3

  • 1Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro, Tokyo, 153-8902, Japan; Graduate School of Integrated Science for Life, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, Hiroshima, 739-8526, Japan.

Analytical biochemistry
|December 29, 2023
PubMed
概括

微生物辅助毛细体电泳 (MACE) 有效地将-寡核酸合物从DNA编码的化学库中分离出来. 这种方法提高了在药物发现中识别特定配体的选择压力.

关键词:
用DNA编码的化学图书馆 (DEL)微生物辅助毛细血管电泳 (MACE) 技术酸-寡核酸合物 (POC) 的使用有效地进行分区.

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Author Spotlight: Detecting Low-Abundant Host Cell Proteins in Drug Products Using Enrichment Beads and Limited Digestion09:45

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