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热冲击蛋白质,氧化应激和抗氧化剂在单驼中
Arash Omidi1, Saeed Nazifi2, Mehdi Rasekh3
1Department of Animal Health Management, School of Veterinary Medicine, Shiraz University, Shiraz, Iran. aomidi@shirazu.ac.ir.
Tropical animal health and production
|December 29, 2023
概括
驼的热冲击蛋白 (HSP) 是适应沙漠热量的关键. 较高的HSP水平与氧化应激相关,显示驼.
科学领域:
- 动物学 动物学
- 环境生理学环境生理学
- 生物化学 生化学
背景情况:
- 单驼 (Camelus dromedarius) 具有在恶劣的沙漠环境中生存的显著生理适应.
- 热应激显著影响动物生理学,需要适应性机制来保护细胞和生存.
- 了解这些适应对于干旱和半干旱地区的牲畜管理至关重要.
研究的目的:
- 在雌性单驼中确定热冲击蛋白 (HSP),生理参数,矿物度,总抗氧化能力 (TAC) 和甲酸 (MDA) 的参考值.
- 调查这些参数在不同地理区域和不同年龄组的变化.
- 为了阐明HSP,氧化应激标记 (MDA) 和抗氧化能力 (TAC) 在热应激驼之间的关系.
主要方法:
- 血液样本从90只健康的雌性驼中收集,这些驼来自伊朗扎博尔的五个不同的地理区域.
- 分析包括使用标准套件和方法量化HSP30,HSP40,HSP70,HSP90,TAC和MDA.
- 使用参考价值顾问 (RVA) 建立了HSP的参考间隔.
主要成果:
- 在HSP,MDA和TAC水平 (P<0.05) 中观察到显著的区域差异,表明不同的适应策略.
- 在HSP和MDA水平 (0.7540.884) 之间发现了强烈的正相关性,这表明HSP是对热应激诱导的氧化应激的反应.
- 在TAC和HSP水平 (0.660至0.820) 之间存在显著的负相关性,突出了抗氧化剂在减轻热应激方面的作用.
结论:
- 热冲击蛋白质在保护驼免受热引起的细胞损伤方面发挥着至关重要的作用.
- 在气候恶劣的地区,HSP水平升高表明驼对热应激的适应性反应.
- 环境因素显著影响HSP的生产,加强了它们在驼对极端温度的抵抗力方面的重要性.
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