鼻腔前庭状细胞癌:一个多中心的观察队列研究
Francesca Pirola1,2, Davide Di Santo3, Mario Turri-Zanoni4,5
1Department of Biomedical Sciences, Humanitas University, Milan, Italy.
The Laryngoscope
|December 29, 2023
概括
分析了鼻前庭状细胞癌 (NV-SCC) 的手术结果. 目前的分期系统不能有效预测NV-SCC患者的预后,年龄和入侵预测生存率.
科学领域:
- 头部和部手术 头部和部手术
- 在瘤学瘤学.
- 手术病理学手术病理学
背景情况:
- 鼻前庭状细胞癌 (NV-SCC) 是罕见的,由于复杂的解剖学而具有挑战性.
- 对NV-SCC的最佳治疗策略和分期系统尚未得到充分确立.
研究的目的:
- 分析初级NV-SCC手术治疗的患者的瘤结局.
- 确定影响NV-SCC生存的预后因素.
主要方法:
- 在10年内进行的回顾性,多中心的观察性研究.
- 包括接受了初级NV-SCC的前期手术的患者.
- 使用卡普兰-梅尔和后勤回归来分析生存率,并根据当前系统进行分期.
主要成果:
- 分析了71名患者,平均随访时间为38个月.
- 三年生存率:整体86.5%,疾病特异性90.3%,无疾病74.2%.
- 年龄,围神经侵袭和淋巴血管侵袭是显著的预后因素.
结论:
- 目前的分期系统对于手术治疗NV-SCC的分层预后是不够的.
- 年龄和特定的入侵类型是生存结果的关键预测因素.
更多相关视频
07:29Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
11.5K
06:15Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
1.2K
相关概念视频
Cranial Bones: Lateral View
The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Nose and Nasal Cavity
The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
