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在化品中使用的三基三利酸盐安全性评估

Monice M Fiume1, Wilma F Bergfeld2, Donald V Belsito2

  • 1Cosmetic Ingredient Review Senior Director.

International journal of toxicology
|December 30, 2023
PubMed
概括

化品成分安全专家小组评估了用于化品的五种试基三利酸盐. 这些成分在当前度下是安全的,以避免皮肤刺激.

关键词:
化品 化品 化品安全的安全的安全的安全的安全.三利/卡普里尔三利化物三基三甲酸的使用方法三乙基基三甲酸三二甲基三二甲酸三聚二甲基三聚酸.

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Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...