[在COVID-19后诊断肺功能障碍时脉冲振荡计的可能性]
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Updated: Jul 6, 2025

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Conducting Respiratory Oscillometry in an Outpatient Setting
Published on: April 8, 2022
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O I Savushkina1,2, P A Astanin3,4, G V Nekludova2,5
1Burdenko Main Military Clinical Hospital.
Terapevticheskii arkhiv
|December 30, 2023
概括
脉冲振荡计 (IOS) 有效地识别小呼吸道功能障碍,并预测COVID-19后的限制性模式和扩散障碍. 这种独立于努力的方法有助于评估COVID-19后的肺机械.
科学领域:
- 肺部病理学 肺部病理学
- 呼吸系统医学 呼吸系统医学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 脉冲振荡计 (IOS) 是一种成熟的,独立于努力的方法,用于评估肺机械.
- 后COVID-19呼吸道并发症,包括小呼吸道功能障碍和肺部体积变化,是一个日益严重的临床问题.
研究的目的:
- 研究IOS在COVID-19感染后的肺机械特征的诊断实用性.
- 在COVID-19后的患者中,将IOS参数与螺旋计,身体囊造影和扩散能力 (DLco) 相关联.
主要方法:
- 一组315名患者,平均年龄为48岁,被评估为COVID-19发病后50天的中位数.
- 进行了标准的肺功能测试,包括螺旋测量,身体囊造影,DLco和IOS.
- 统计分析包括描述性统计,相关性和后勤回归来确定风险因素.
主要成果:
- 虽然螺旋测量和体积积测量在很大程度上是正常的,但61%的患者表现出DLco.co.降低.
- IOS参数,如反应率面积 (AX) 和抵抗异质性 (Rrs5-Rrs20) 在很大一部分患者中升高.
- AX和Rrs5-Rrs20的增加与DLco和肺总容量 (TLC) 降低的风险显著增加有关.
结论:
- IOS可以检测到小的呼吸道功能障碍,通过增加的AX或Rrs5-Rrs20.20表示.
- IOS参数对于识别COVID-19后患有限制性肺模式和扩散障碍的患者有价值.
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