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葡萄糖皮质醇诱导的TNF受体家族相关的蛋白质功能作为一种对类异氨基菌的共刺激分子

Tomoya Narita1,2, Yusuke Murakami1,2, Takashi Ishii2

  • 1Department of Pharmacotherapeutics, Faculty of Pharmacy, Musashino University, Shinmachi 1-1-20, Nishitokyo-shi, Tokyo 202-8585, Japan.

Journal of leukocyte biology
|December 30, 2023
PubMed
概括

葡萄糖皮质类药物诱导的瘤亡因子受体家族相关蛋白 (GITR) 作为一种辅助刺激分子作用于eosinophils. 在过敏疾病模型中,GITR的参与增强了像IL-4,IL-6和IL-13这样的炎症性细胞因子的分泌.

关键词:
作为TNF受体家族的一员.这是一种共刺激分子分子.细胞因子细胞因子埃奥西诺菲尔是一种埃奥西诺菲尔.

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
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