兴奋的神经相关物:腹腔后侧核-全球短暂的协同激活
Junrong Han1, Qiuyou Xie2, Xuehai Wu3
1Key Laboratory of Brain, Cognition and Education Sciences, Ministry of Education, Institute for Brain Research and Rehabilitation, Guangdong Key Laboratory of Mental Health and Cognitive Science, South China Normal University, Guangzhou 510631, China.
Cell reports
|December 30, 2023
概括
研究了意识,兴奋和意识的神经机制. 腹腔后侧核 (VPL) 和全球大脑活动的协同激活对于各种意识状态中的兴奋至关重要,但不是意识.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 意识研究 意识研究
背景情况:
- 意识包括唤醒和意识,有不清楚的神经支.
- 全球大脑活动,通过血液氧化水平依赖 (BOLD) 信号测量,随着兴奋水平的波动.
研究的目的:
- 研究区分唤醒和意识的神经机制.
- 检查腹后侧核 (VPL) 在意识中的作用.
主要方法:
- 在不同的兴奋和意识状态 (清醒,睡眠,麻醉,UWS) 中对比BOLD信号.
- 分析VPL和全球大脑活动之间的协同激活模式.
主要成果:
- 与清醒状态相比,在低唤醒/意识状态 (睡眠,麻醉) 中观察到的VPL-全球联合激活的减少.
- 在不响应的清醒综合征 (UWS) 患者 (高兴奋,没有意识) 中,高VPL-全球联合激活仍然存在.
- 与UWS相比,在REM睡眠 (低唤醒,高意识) 中减少了VPL-全球协同激活.
结论:
- VPL-全球协同激活对于唤醒至关重要.
- 为了提高意识,不需要VPL-全球协同激活.
- 这些发现区分了兴奋和意识的神经相关物.
相关概念视频
Sympathetic Activation
5.3K
The sympathetic division can influence tissues and organs by releasing norepinephrine at peripheral synapses and distributing epinephrine and norepinephrine through the bloodstream. In times of crisis or stress, sympathetic activation occurs, which is regulated by sympathetic centers in the hypothalamus. As a result, sympathetic activation prepares the body for physical exertion, rapid ATP production, and heightened alertness, allowing individuals to respond effectively to challenging or...
5.3K
Functional Brain Systems: Reticular Formation
1.9K
The reticular formation is a complex network of gray and white matter located within the brainstem extending from the medulla to the midbrain.
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
1.9K
Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla
1.3K
The sympathetic pathways of the collateral ganglia and adrenal medulla serve unique but interconnected roles in the sympathetic response.
Collateral Ganglia
Sympathetic preganglionic axons reach the collateral ganglia along the route of splanchnic nerves. These nerves bypass the sympathetic trunk and communicate with sympathetic postganglionic neurons housed in the prevertebral ganglia. These ganglia supply the organs of the abdominopelvic cavity.
The greater splanchnic nerve, formed by the...
Collateral Ganglia
Sympathetic preganglionic axons reach the collateral ganglia along the route of splanchnic nerves. These nerves bypass the sympathetic trunk and communicate with sympathetic postganglionic neurons housed in the prevertebral ganglia. These ganglia supply the organs of the abdominopelvic cavity.
The greater splanchnic nerve, formed by the...
1.3K
Physiological Theories: James-Lange Theory of Emotion
612
The James-Lange theory of emotion, proposed by William James and Carl Lange in the late 19th century, asserts that emotions are the result of physiological reactions to external stimuli. Contrary to the traditional view, which suggests that emotions directly arise from the perception of stimuli, this theory proposes that emotions occur as a consequence of the body's responses to such stimuli. According to this framework, an emotional experience is a cognitive interpretation of physiological...
612
Physiology of Emotion
854
The physiology of emotions is a multifaceted process involving the autonomic nervous system, brain structures, hormones, and neurotransmitters. This intricate interplay dictates how emotions manifest in the body and influence behavior.
Autonomic Nervous System
The autonomic nervous system (ANS) plays a critical role in emotional responses by regulating involuntary physiological functions. It consists of two main components: the sympathetic and parasympathetic systems. The sympathetic system...
Autonomic Nervous System
The autonomic nervous system (ANS) plays a critical role in emotional responses by regulating involuntary physiological functions. It consists of two main components: the sympathetic and parasympathetic systems. The sympathetic system...
854
Functional Brain Systems: Limbic System
2.8K
The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
2.8K


