生活质量与神经性肠道症状之间的关联由肠道管理计划在脊柱二叉脊柱
Nadia Valeska Halstead1, Josephine Hirsch1, Ilina Rosoklija1
1Division of Urology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL.
Urology
|December 30, 2023
概括
神经性肠功能障碍 (NBD) 的严重程度,而不是特定的管理计划,显著影响脊柱裂变 (SB) 患者的生活质量 (QOL). 有效的NBD管理是改善整体QOL的关键.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 神经科学是一个神经科学.
- 生活质量研究 研究 生命质量研究
背景情况:
- 脊椎裂 (SB) 经常导致神经性肠功能障碍 (NBD),显著影响患者的生活质量 (QOL).
- 存在各种肠道管理计划,但它们对QOL和NBD严重程度的比较影响尚未完全理解.
研究的目的:
- 在SB患者的不同肠道管理计划中比较肠道特定的QOL,整体QOL和NBD严重程度.
- 为了确定与SB患者的QOL最强烈相关的因素NBD.
主要方法:
- 173名SB患者 (≥12岁) 的回顾性横截面研究.
- 使用修改后的Peristeen NBD问卷和儿科全球健康问卷.
- 使用多变量模型分析了结果和肠道管理之间的关联 (阴囊,保守,没有).
主要成果:
- 不同的肠道管理计划之间没有发现肠道特定或整体QOL的显著差异.
- 保守的管理与阴囊相比,与更糟糕的肠道症状严重程度有关.
- 较大的NBD症状严重程度与较低的整体QOL相关.
结论:
- NBD症状严重程度,而不是特定的肠道管理计划,是SB患者QOL的主要决定因素.
- 在管理NBD症状方面,肠道计划的有效性比程序的类型对QOL更为关键.
- 根据NBD严重程度调整干预措施对于优化QOL至关重要.
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