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肝脏GRK2对于葡萄糖平衡和其他关键代谢参数在小鼠中是不可或缺的

Antwi-Boasiako Oteng1, Srinivas Pittala1, Andrea Kliewer2

  • 1Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892, USA.

Molecular metabolism
|December 30, 2023
PubMed
概括

肝细胞G蛋白结合受体 (GPCR) 激酶2 (GRK2) 不是维持葡萄糖平衡或小鼠代谢功能的必要条件. 抑制代谢障碍的GRK2应该针对其他组织.

关键词:
G蛋白结合受体的受体是G蛋白结合受体的受体.葡萄糖耐受性是一种耐受性.淘汰赛小鼠 淘汰赛小鼠肝脏 肝脏 肝脏 肝脏代谢过程中的代谢.

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Carbohydrates consumed through foods are converted into glucose, a crucial energy source for the body. In the prandial state, high blood glucose levels stimulate the secretion of insulin from the pancreas. Insulin inhibits hepatic glucose production and stimulates glucose uptake and metabolism by muscle and adipose tissue. The excess glucose is converted into glycogen and stored in the liver and muscles.
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