从反动物的鼻子中分离出来的金黄色葡萄球菌的多样性
Igor Loncaric1, Helga Keinprecht1,2, Emmanuel Irimaso3
1Institute of Microbiology, University of Veterinary Medicine Vienna, Vienna 1210, Austria.
Journal of applied microbiology
|December 30, 2023
概括
黄金葡萄球菌 (Staphylococcus aureus) 是导致乳腺炎的原因,在卢旺达的反动物中发现. 一些菌株与人类共享,对牲畜处理者构成动物感染风险,并强调卫生.
科学领域:
- 兽医微生物学 兽医微生物学
- 动物传播疾病 动物传播疾病
- 分子流行病学分子流行病学
背景情况:
- 黄金葡萄球菌 (Staphylococcus aureus) 是人类和动物健康的重要病原体.
- 食动物可以充当金黄色菌的储存体,可能有助于其传播.
研究的目的:
- 调查卢旺达从反动物中分离出来的金黄色葡萄球菌的遗传多样性和特征.
- 评估在牲畜中发现的黄金菌的潜在动物传染性影响.
主要方法:
- 从牛,山羊和绵羊的鼻子抽样中分离的金黄色细菌的表型和基因型特征.
- 斯帕类型和克隆复合体 (CC) 分析以确定遗传相关性.
- 检测毒性基因,包括潘顿-瓦伦丁白血 (PVL) 和毒性冲击综合征毒素 (tst-1).
主要成果:
- 从454个鼻子抽样中鉴定出30个S. aureus分离体.
- 隔离物对青素和/或四环素表现出耐药性.
- 确定了八种属于六个CC的spa类型,其中一些血统已知可以殖民人类.
- 检测Panton-Valentine leucocidin,牛 leucocidin和有毒冲击综合征毒素变体的基因.
结论:
- 卢旺达的食动物中含有与乳腺炎相关的黄金菌株,包括在人类中也发现的.
- 共同血统的存在突显了动物感染风险,特别是在与牲畜密切接触的个体.
- 这些发现强调了在畜牧业管理中实施严格的卫生做法的重要性.
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