一种来自Aspergillus cibarius的病毒,具有阿尔法和贝塔克里索病毒的特征
Tobias Lutz1, Gitta Jutta Langer2, Cornelia Heinze3
1Institute of Plant Science and Microbiology, University of Hamburg, Molecular Phytopathology, Ohnhorststr. 18, 22609, Hamburg, Germany.
Virus genes
|December 30, 2023
概括
一种新型病毒,Aspergillus cibarius chrysovirus 1 (AcCV1),从与灰树死亡相关的真菌中分离出来. 这种病毒具有独特的基因组结构和基因组定位,表明它是氏病毒家族中的新属.
科学领域:
- 菌类学 菌类学是指菌类学.
- 病毒学 病毒学
- 植物病理学 植物病理学
背景情况:
- 研究的是Aspergillus cibarius,一种与Fraxinus excelsior L. (灰树) 相关的真菌.
- 真菌病毒可以影响宿主植物的相互作用和疾病的发展.
研究的目的:
- 为了隔离和描述一个来自Aspergillus cibarius的新型病毒.
- 为了确定新型病毒在Chrysoviridae家族中的家族遗传关系.
主要方法:
- 从Aspergillus cibarius中分离和净化病毒.
- 双链RNA (dsRNA) 分段的基因组测序.
- 通过测序和凝电泳分析进行蛋白质分析.
- 基因分析基于病毒RdRp和结构蛋白.
主要成果:
- 一种新型病毒,Aspergillus cibarius chrysovirus 1 (AcCV1),被分离出来,具有一个三段的dsRNA基因组 (3683 bp, 3093 bp, 2902 bp).
- 病毒被包裹在同度粒子 (~35 nm) 中,并编码病毒RNA依赖的RNA聚合酶 (P1) 和两个结构蛋白 (P2,P3).
- 遗传学分析将AcCV1置于克里索维拉家族中,与现有的属不同,表明了一个新的属",Gammachrysovirus".
结论:
- 阿斯珀吉勒斯·西巴里乌斯·克里索病毒1代表了一种具有独特基因组和遗传学特征的新型克里索病毒.
- 这些发现支持建立一个新属"Gammachrysovirus",以适应AcCV1.
- 需要进一步的研究来了解AcCV1在Fraxinus excelsior necrosis中的作用.
相关概念视频
Rous Sarcoma Virus (RSV) and Cancer
5.1K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
5.1K
Viral Structure
62.3K
Viruses are extraordinarily diverse in shape and size, but they all have several structural features in common. All viruses have a core that contains a DNA- or RNA-based genome. The core is surrounded by a protective coat of proteins called the capsid. The capsid is composed of subunits called capsomeres. The capsid and genome-containing core are together known as the nucleocapsid.
62.3K
Viral Recombination
23.4K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.4K
Retroviruses
12.3K
Retroviruses and retrotransposons both insert copies of their genetic elements into the genome of the host cell. Thus, the viral genes are passed on when the host genome is replicated or translated. A typical retroviral DNA sequence contains 3-4 genes that encode the different proteins required for its structural assembly and function as a molecular parasite. This DNA is transcribed into a single mRNA, which is very similar in structure to conventional mRNAs, i.e., it is capped at the 5’...
12.3K
Retrovirus Life Cycles
46.0K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
46.0K


