怀孕期间父母的SARS-CoV-2感染与胎儿生长限制之间的关联
Melanie Mitta1, Lauren Holt1, Suchitra Chandrasekaran1
1Department of Obstetrics and Gynecology, Emory University School of Medicine, Atlanta, GA, USA.
Journal of perinatal medicine
|December 31, 2023
概括
这项研究发现,怀孕期间的SARS-CoV-2感染与胎儿生长限制 (FGR) 之间没有联系. 结果表明,仅仅COVID-19状态并不需要额外的胎儿生长超声波.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 围产儿医学 围产儿医学
背景情况:
- 母性病毒感染与胎儿生长限制 (FGR) 有关.
- SARS-CoV-2 感染对怀孕结果,特别是 FGR 的影响需要进一步调查.
研究的目的:
- 调查怀孕期间的SARS-CoV-2感染与FGR发生率之间的关联.
- 评估二次结果,包括孕前症,对于妊娠年龄来说小 (SGA),以及出生体重.
主要方法:
- 一项由妊娠年龄和SARS-CoV-2 PCR测试月份 (2020年4月-2022年7月) 匹配的前性队列研究.
- 纳入标准:怀孕32周的SARS-CoV-2 PCR测试和第三个月的超声波.
- 主要结局:FGR诊断;次要结局:孕前,SGA,出生体重. 通过单变量分析,奇平方测试和逻辑回归来分析.
主要成果:
- 队列包括102名SARS-CoV-2阳性和103名阴性孕妇.
- FGR比率相似:17.8% (积极) 和19.42% (负).
- 在人口统计,FGR,SGA率或出生体重方面没有发现显著差异. 孕前率显示出统计差异,但几率并不显著.
结论:
- 在这个机构,怀孕期间的SARS-CoV-2感染与FGR无关.
- 研究结果支持,仅仅SARS-CoV-2感染状态并不需要进行额外的胎儿生长超声波评估.
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