Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

164
Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
164
Inflammation01:38

Inflammation

53.4K
Overview
53.4K
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

2.8K
2.8K
Lipid-Lowering Drugs: Statins and Miscellaneous Agents01:20

Lipid-Lowering Drugs: Statins and Miscellaneous Agents

665
Hyperlipidemia, a medical condition often referred to as high cholesterol, is characterized by abnormally elevated levels of lipids in the bloodstream. When present in excess, these lipids, specifically cholesterol and triglycerides, can lead to serious health complications, often involving cardiovascular diseases. Illnesses like atherosclerosis, heart attacks, and pancreatitis have all been linked to untreated hyperlipidemia. This means controlling and regulating cholesterol and triglyceride...
665
Asymmetric Lipid Bilayer01:35

Asymmetric Lipid Bilayer

7.2K
Biological membranes show uneven distribution of different types of lipids in the inner and outer layers, resulting in transverse asymmetric membranes. The treatment of the erythrocyte membrane with the enzyme phospholipase confirmed the asymmetric nature of the lipid bilayer. The enzyme hydrolyzes lipids into fatty acids and hydrophilic groups. The phospholipase acts only on the outer layer of the membrane, while the inner layer remains intact. The phospholipase treatment resulted in 80%...
7.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Tackling Therapeutic Inertia on Mineralocorticoid Receptor Antagonist Adoption in Heart Failure.

The Journal of the Association of Physicians of India·2026
Same author

Loop Diuretics Unique Mechanism of Action.

The Journal of the Association of Physicians of India·2024
Same author

CSI clinical practice guidelines for dyslipidemia management: Executive summary.

Indian heart journal·2023
Same author

Safety and Feasibility of Ultrasound-Guided Access for Coronary Interventions through Distal Left Radial Route.

Journal of interventional cardiology·2022
Same author

Acute coronary syndrome caused by infliximab in a patient with ankylosing spondylitis.

International journal of rheumatic diseases·2013
Same author

Fractional flow reserve: intracoronary versus intravenous adenosine induced maximal coronary hyperemia.

Indian heart journal·2013

相关实验视频

Updated: Jul 6, 2025

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
07:29

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein

Published on: October 12, 2017

9.3K

脂蛋白a - Lp (a) 在

Tapan Ghose1

  • 1Director and Head of Cardiology, Fortis Flt Lt Rajan Dhall Hospital New Delhi, 11-0070, India.

Indian heart journal
|December 31, 2023
PubMed
概括

升高的脂蛋白 (Lp) 是动脉样硬化心血管疾病 (ASCVD) 的关键遗传风险因素. 建议测量Lp (a),特别是在有心脏病家族史的情况下,以指导风险管理.

科学领域:

  • 心脏病学 心脏病学
  • 遗传学 遗传学 是一个
  • 预防医学 预防医学

背景情况:

  • 脂蛋白 (Lp) 是动脉样硬化心血管疾病 (ASCVD) 的独立,基因决定的风险因素.
  • 大约20%的全球人口和25%的印度人有升高的Lp (a) 水平 (>50 mg/dL或>125 nmol/L).
  • 升高的Lp (a) 与心肌梗塞,中风,心力衰竭和通过促炎和促动脉动脉的机制增加的死亡风险有关.

研究的目的:

  • 要突出脂蛋白 (Lp) 作为动脉样硬化心血管疾病 (ASCVD) 的因果风险因素的重要性.
  • 强调升高的Lp (a) 的患病率及其与心血管事件和死亡率的关联.
  • 讨论目前对Lp (a) 测量,级联测试和新兴治疗策略的建议.

主要方法:

  • 流行病学,全基因组关联和门德尔随机化研究的综述.
  • 在各种临床环境和人群中分析Lp(a) 水平,包括最近印度对冠状动脉疾病 (CAD) 患者的研究.
  • 评估新兴的Lp (a) 降低疗法,如PCSK9抑制剂,Inclisiran和Pelacarsen.

主要成果:

  • 流行病学和遗传学研究证实Lp (a) 是一种因果性ASCVD风险因素.
  • 升高的Lp (a) 水平与心肌梗塞,中风和死亡率的增加有关.
关键词:
脂蛋白 (a) 是一种蛋白质(一) 一个 (一) 一个 (一) 一个非传统的CAD风险因子

更多相关视频

Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation
06:47

Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation

Published on: January 28, 2021

11.2K
Click-Chemistry Based Fluorometric Assay for Apolipoprotein N-acyltransferase from Enzyme Characterization to High-Throughput Screening
07:37

Click-Chemistry Based Fluorometric Assay for Apolipoprotein N-acyltransferase from Enzyme Characterization to High-Throughput Screening

Published on: May 13, 2020

2.0K

相关实验视频

Last Updated: Jul 6, 2025

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
07:29

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein

Published on: October 12, 2017

9.3K
Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation
06:47

Isolation and Analysis of Plasma Lipoproteins by Ultracentrifugation

Published on: January 28, 2021

11.2K
Click-Chemistry Based Fluorometric Assay for Apolipoprotein N-acyltransferase from Enzyme Characterization to High-Throughput Screening
07:37

Click-Chemistry Based Fluorometric Assay for Apolipoprotein N-acyltransferase from Enzyme Characterization to High-Throughput Screening

Published on: May 13, 2020

2.0K
  • 最近的一项印度研究发现,在CAD患者中,升高的Lp (a) 与严重血管学疾病相关,特别是在患有家族性高胆固醇血症 (FH) 的年轻患者中.
  • 结论:

    • 脂蛋白 (Lp) 是动脉样硬化心血管疾病 (ASCVD) 的关键性,遗传性风险因素,需要终身监测.
    • 建议一生至少进行一次Lp (a) 的测量,对具有高Lp (a) 或早发ASCVD家族病史的个人进行级联测试.
    • 虽然综合性风险因素管理至关重要,但像Pelacarsen这样的新型Lp (a) 降低疗法显示出降低心血管风险的巨大潜力.