相关实验视频
Updated: Jul 6, 2025
09:16
Assessment of Kidney Function in Mouse Models of Glomerular Disease
Published on: June 30, 2018
17.7K
在糖尿病病中对淋巴结膜纤维沉积物的超结构检查
Sophie I Nagelkerken1, Peter H Neeskens1, Joris I Rotmans2
1Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.
Laboratory investigation; a journal of technical methods and pathology
|December 31, 2023
概括
糖尿病脏病经常出现球纤维状沉积物,在诊断中经常错过. 这些沉积物类似于纤维状丸炎的沉积物,可能会使脏活检的解释复杂化.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 病理学 病理学 病理学
- 电子显微镜电子显微镜
背景情况:
- 在糖尿病脏病中很少有报道的淋巴细胞纤维沉积物.
- 没有大规模的超结构性研究评估了糖尿病病中的这些沉积物.
研究的目的:
- 调查糖尿病病中膜纤维沉积物的流行率和超结构特征.
- 为了比较这些沉积物与纤维状结膜病变中发现的沉积物.
主要方法:
- 传输电子显微镜 (TEM) 用于评估55名糖尿病病患者和18名健康捐赠者的活检.
- 活检被评估使用光显微镜和免疫光学.
主要成果:
- 在所有糖尿病病例中都存在小纤维状结构 (10 ± 1 nm).
- 在35例中发现了较大的纤维状结构 (23 ± 5 nm或30 ± 7 nm).
- 小型和中型纤维状体类似于纤维状结膜病的纤维状纤维状体.
结论:
- 在糖尿病病中,淋巴结膜纤维沉积比以前认为的更为常见.
- 超结构上的相似性与纤维状丸膜炎的相似性可能会导致诊断挑战.
- 当在电子显微镜上观察到纤维状沉积物时,应考虑糖尿病病.
相关概念视频
01:20Renal Corpuscle
2.3K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
2.3K
01:10Nephrons
2.5K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
2.5K