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儿童医疗保健中的设备相关血栓和出血:一个元分析
Amanda Ullman1,2,3, Areum Hyun1, Victoria Gibson1,2
1School of Nursing, Midwifery and Social Work, The University of Queensland, Queensland, Australia.
Hospital pediatrics
|December 31, 2023
概括
侵袭性器械在儿童中存在血栓形成和出血的风险. 中枢静脉接入装置的症状VTE率为4%,而心室辅助装置和ECMO显示出高的主要出血率.
科学领域:
- 儿科医疗保健 儿科医疗保健
- 医疗器械 医疗器械
- 血栓形成和出血并发症
背景情况:
- 侵入性设备在儿科护理中至关重要,但会带来血栓形成和出血的风险.
- 这些并发症的发生率因设备类型而异,需要进一步研究.
研究的目的:
- 估计使用侵入性器械的儿科患者中血栓和出血并发症的综合比例和发病率.
- 提供特定于设备的数据,以告知临床实践和风险评估.
主要方法:
- 在多个数据库 (Medline,CINAHL,Embase等) 中进行系统搜索. 是进行的.
- 包括2011年1月至2022年6月期间发表的队列研究和试验,重点关注具有侵入性设备的儿科住院病例.
- 根据MOOSE数据抽象和质量评估指南,采用了元分析技术.
主要成果:
- 中枢静脉接入装置 (CVAD) 是66%的研究的重点.
- 与CVAD相关的症状静脉血栓塞栓症 (VTE) 为4% (发生率为0.03/1000设备日),而无症状VTE为10% (发生率为0.25/1000设备日).
- 心室辅助器械 (VAD) 和体外膜氧化器 (ECMO) 显示出大量出血的高率 (分别为28%和67%).
结论:
- 这项研究提供了对儿童设备相关血栓和出血的全面估计.
- 研究结果可以为具有侵入性设备的儿科患者的临床决策,风险分层和监测策略提供信息.
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