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Updated: Jul 6, 2025

Rapid Synthesis and Screening of Chemically Activated Transcription Factors with GFP-based Reporters
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在CHO细胞中使用具有雌激素结合域的人工转录激活剂诱导转基因表达

Md Rashidur Rahman1, Yoshinori Kawabe1, Kozumi Suzuki1

  • 1Department of Chemical Engineering, Faculty of Engineering, Kyushu University, Fukuoka, Japan.

Biotechnology journal
|December 31, 2023
PubMed
概括

这项研究引入了一种新的系统,用于控制中国仓鼠卵巢 (CHO) 细胞中的生物制药生产. 该技术精确地乘以重组蛋白的表达,使治疗抗体的高效和连续制造成为可能.

关键词:
在CHO细胞中.人工转录因子的人工转录因子雌激素受体的受体是雌激素受体.可诱导的转基因表达.在scFv-Fc抗体中.

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