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Updated: Jul 6, 2025

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
04:41

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration

Published on: January 9, 2020

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在全基因组关联研究中使用贝叶斯变异性尖峰和板块模型,寻找与双相情感障碍相关的位置

Maryam Kazemi Naeini1, Mahdi Akbarzadeh2, Iraj Kazemi3

  • 1Department of Biostatistics and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.

Annals of human genetics
|January 1, 2024
PubMed
概括

这项研究引入了一种稀疏的贝叶斯学习模型,以在小样本中识别双相情感障碍 (BD) 的遗传变异. 该模型克服了传统的全基因组关联研究 (GWAS) 的统计局限性,揭示了新的遗传关联.

关键词:
贝叶斯的变量推理推理在GWAS中,GWAS就是GWAS.双相情感障碍是双相情感障碍的一种疾病.尖和板模型的模型.

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A Pipeline using Bilateral In Utero Electroporation to Interrogate Genetic Influences on Rodent Behavior06:59

A Pipeline using Bilateral In Utero Electroporation to Interrogate Genetic Influences on Rodent Behavior

Published on: May 21, 2020

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