与相关的风险因素与脑血管疾病相关:系统性审查和元分析
Ana Paula Mafla-Mendoza1, Esteban David Paredes-Urbano1, Enrique Gea-Izquierdo1,2,3
1Pontifical Catholic University of Ecuador, Faculty of Medicine, Quito, Ecuador.
Neuropsychiatric disease and treatment
|January 1, 2024
概括
脑卒中后 (PSE) 的风险因出血,皮质干扰和早期发作而增加. 目前的预测工具需要进一步精细化,以便在中风患者中临床应用.
科学领域:
- 神经学 神经学
- 发病学 (Epileptology) 是一个专业的学科.
- 临床流行病学 临床流行病学
背景情况:
- 脑卒中是导致神经障碍的主要原因,也是导致成人发的重要因素.
- 确定中风后 (PSE) 的可靠预测因素仍然是一个临床挑战.
- 现有的PSE预测模型往往缺乏跨不同中风病因的全面验证.
研究的目的:
- 系统地审查和比较现有的成年患者中风后 (PSE) 的预测尺度.
- 确定与中风后发作的关键临床因素.
- 评估PSE不同预测工具的性能和偏差风险.
主要方法:
- 2010年至2020年间发表的研究的系统审查和元分析.
- 在主要的生物医学数据库 (PubMed,Scopus,EMBASE等) 进行的搜索. ) 的情况.
- 包括16项研究,包括298,694名中风患者,其中5590人经历了晚期 (LS).
主要成果:
- 出血性中风,皮质干涉和早期发作与晚期发作 (LS) 的风险增加显著相关.
- 选择得分显示出良好的预测能力 (AUC:0.77) 缺血性中风与偏差的低风险.
- CAVE评分显示出对出血性中风的足够预测能力 (AUC:0.81),但偏差风险不确定.
结论:
- 出血,皮质干扰和早期发作是发作后的关键风险因素.
- 年龄,传统血管风险因素和功能评估在预测PSE方面没有统计学意义.
- 需要进行进一步的研究,以开发和完善适用于所有类型中风的PSE强大的预测工具.
相关概念视频
Arteries of the Lower Limbs
190
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
190
Seizures: Classification
368
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
368


