评估深度学习模型对胸部X射线图的COVID-19分类:图像采集技术和临床因素之间的比较
Mena Shenouda1, Isabella Flerlage2, Aditi Kaveti3
1The University of Chicago, Committee on Medical Physics, Department of Radiology, Chicago, Illinois, United States.
Journal of medical imaging (Bellingham, Wash.)
|January 1, 2024
概括
一个深度学习模型在较新的数据集上从胸部X射线中对COVID-19进行分类时表现较差. 病毒变异和疫苗接种状况等因素不能完全解释精度的下降,这表明潜在的过拟合.
科学领域:
- 医疗成像医学成像
- 人工智能的人工智能
- 放射学 放射学是一门学科.
背景情况:
- 深度学习模型越来越多地用于医学图像分析.
- 从胸部X射线图 (CXR) 中对冠状病毒病 (COVID-19) 的分类是一个关键的应用.
- 评估模型在不同患者群体和时间段的概括性是必不可少的.
研究的目的:
- 用CXRs评估预训练的深度学习模型在分类COVID-19阳性与阴性患者中的表现.
- 调查图像采集参数,临床因素和患者人口统计学对模型性能的影响.
- 将原始数据集的模型性能与更大,更当前的测试集进行比较.
主要方法:
- 在9860名患者的原始数据集 (标准和软组织CXR) 上训练了DenseNet-121架构.
- 用三个分类算法评估模型性能:标准图像,软组织图像和通过特征融合的组合.
- 一个单独的,更大的5893名患者的当前测试组,反映了不同的病毒变体和免疫状态,用于验证.
主要成果:
- 该模型在接收器运行特征曲线 (ROC AUC) 下的面积为标准图像达到0.67,软组织图像达到0.65,结合切割图像达到0.67.
- 与原始测试组相比,当前测试组的性能明显低于原始测试组.
- 获取日期,病毒变异,免疫状态,疾病严重程度,年龄和性别分布等因素并不能完全解释性能差异.
结论:
- 预训练的深度学习模型在最近和多样化的胸部X射线测试组上表现较差.
- 观察到的性能下降可能归因于模型过拟合和缺乏对新数据的概括性.
- 需要进一步的研究,以了解和减轻COVID-19检测的深度学习模型中的性能退化.
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