关于在轻度COVID-19疾病后大学受过教育的患者认知功能障碍的初步发现
Jonas Stenberg1,2, Stina Hedström1,2, Gabriela Markovic1,2
1Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.
Archives of rehabilitation research and clinical translation
|January 1, 2024
概括
认知缺陷,包括口头学习和记忆方面的问题,在COVID-19后的个人中仍然存在,即使是那些受过高等教育,初始感染轻度的人. 这些发现突显了COVID-19的长期认知影响.
科学领域:
- 神经科学是一个神经科学.
- 传染性疾病 传染性疾病
- 认知心理学 认知心理学
背景情况:
- 后COVID-19状态,或长期COVID,在SARS-CoV-2感染后影响了大量个体.
- 认知功能障碍是经常报告的症状,但其在最初轻微感染的受过高等教育的人群中的程度不太清楚.
研究的目的:
- 为了研究高学历的患者的认知功能,他们经历了COVID-19后的情况.
- 在这个人群中确定受长期COVID影响的特定认知领域.
主要方法:
- 一项前性队列研究在门诊康复诊所进行.
- 用全面的神经心理测试电池评估认知表现,包括记忆,注意力和执行功能的测量.
- 从感染到评估的平均时间为18个月.
主要成果:
- 在口头学习和记忆 (布什克选择性提醒测试) 和选择性注意力 (Ruff 2&7) 中观察到缺陷.
- 大约50%的参与者在口头学习和记忆方面得分低于平均水平.
- 在估计的病前功能时,大多数领域都建议认知缺陷.
结论:
- 后COVID-19状态与认知缺陷有关,即使在具有高教育程度和最初轻微感染的患者中也是如此.
- 长期认知障碍在COVID-19后状态的管理中需要注意.
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