哺乳作为预防早产婴儿支气管肺功能障碍的保护因素
Jose Uberos1,2, Isabel Sanchez-Ruiz1, Elizabeth Fernández-Marin2
1Facultad de Medicina, Universidad de Granada, Granada, Spain.
The British journal of nutrition
|January 2, 2024
概括
非常低出生体重 (VLBW) 婴儿的母乳营养与支气管肺功能障碍 (BPD) 的风险较低有关. 早期母乳摄入显著降低了这些脆弱的新生儿中BPD的患病率和严重程度.
科学领域:
- 新生儿医学 新生儿医学
- 儿童营养学 儿童营养学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 支气管肺功能障碍症 (BPD) 是非常低出生体重 (VLBW) 的早产婴儿的显著并发症.
- 营养干预措施,特别是母乳,可能在缓解BPD发展方面发挥关键作用.
- 了解早期营养对BPD的影响对于改善早产婴儿的结果至关重要.
研究的目的:
- 调查母乳营养与VLBW婴儿BPD的患病率和严重程度之间的关联.
- 为了确定早期摄入母乳 (MOM) 或捐赠奶是否会影响BPD的结果.
- 分析出生后前两周营养摄入量与BPD发展之间的关系.
主要方法:
- 对489名VLBW婴儿 (2008年1月至2021年12月出生) 的回顾性队列研究.
- 在出生后的前两周内收集的关于母乳 (MOM),消毒供体母乳或产前配方奶的摄入量数据.
- 统计分析以评估母乳摄入量与BPD患病率和严重程度之间的关联,包括几率比率 (OR) 和置信区间 (CI).
主要成果:
- 在分析的489名婴儿中,有195名患有某种程度的BPD.
- 中度至重度的BPD与体重增加的减少有关.
- 在出生后的前两周内,优先摄入母乳显示,轻度 (OR 0.16) 和重度 (OR 0.08) BPD的几率在统计学上显著下降.
结论:
- 在产后生命的最初几周内,母乳营养与VLBW婴儿BPD的发病率降低有关.
- 早期摄入母乳可能有助于减轻BPD的严重程度.
- 这些发现强调了促进VLBW婴儿母乳养的重要性,以预防呼吸道并发症.
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