患有支气管炎住院婴儿的氧和目标:一个多中心队列研究
James H B Im1,2, Gita Wahi3, Lucy Giglia3
1Dalla Lana School of Public Health.
对于患有支气管炎的婴儿,医院的氧和目标显示出类似的临床结果. 90%清醒/88%睡眠或90%清醒/睡眠的政策在患者的康复或资源使用方面没有显著差异.
科学领域:
- 儿科 儿科 儿科
- 呼吸系统医学 呼吸系统医学
- 临床结果研究研究
背景情况:
- 支气管炎是婴儿常见的呼吸道感染,通常需要住院治疗.
- 氧和目标是患有支气管炎的住院婴儿的关键管理策略.
- 不同的医院政策存在关于在清醒和睡眠状态期间目标氧和水平.
研究的目的:
- 为了比较两个不同的医院氧和目标政策下住院患有支气管炎的婴儿的临床结果.
- 评估氧和目标 (90%/88% vs. 90%/90%) 与患者的治疗结果之间的关联.
主要方法:
- 一个多中心队列研究,利用随机临床试验的数据.
- 包括患有支气管炎住院的4周至24个月的婴儿.
- 模拟两个氧气和目标政策 (90%清醒/88%睡眠与90%清醒/睡眠) 与临床结果之间的关联.
主要成果:
- 在两个氧和目标群体之间,没有观察到释放时间,补充氧气使用或再访的显著差异.
- 父母工作缺勤率在90%/88%的群体中呈现出更高的趋势 (调整后的几率比,2.41;P = .08).
- 在90%/88%组中,有3名婴儿需要转移到重症监护室,而在90%/90%组中没有婴儿.
结论:
- 医院氧和目标政策的90%清醒/88%睡眠和90%清醒/睡眠导致类似的临床结果的婴儿住院患有支气管炎.
- 这些发现表明,在设定支气管炎治疗的氧和目标方面,存在灵活性.
- 进一步的研究可能会为儿科呼吸护理的最佳氧和目标提供信息.
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