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在检测侵入性导管性乳腺癌时,F-FDG PET/CT和扩散权重成像之间的比较

Aynur Ozen¹, Tarik Sayin², Ozan Kandemir³

¹Department of Nuclear Medicine, Istanbul Bagcılar Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Asia Oceania journal of nuclear medicine & biology

|January 2, 2024

概括

-18-氧葡萄糖 (18F-FDG) PET/CT和扩散权重MRI有效检测侵袭性导管性乳腺癌,原发性瘤和下转移. 与MRI相比,PET/CT对检测转移性淋巴结的特异性更高.

科学领域:

在瘤学瘤学.
放射学放射学是指放射学
核医学是一种核医学.

背景情况:

乳腺癌是女性中最常见的癌症.
准确检测原发性瘤和股转移对于有效的乳腺癌管理至关重要.
比较像18F-FDG PET/CT和扩散权重MRI等成像方式有助于优化诊断策略.

研究的目的:

为了比较18F-FDG吸收模式和明显扩散系数 (ADC) 值在检测原发性侵入性导管性乳腺癌中的有效性.
评估这些成像技术在识别状淋巴结转移中的性能.
探索成像参数 (ADC,SUVmax) 与乳腺癌的病理特征之间的相关性.

主要方法:

研究包括39名患者的40个乳腺癌病变.
患者使用18F-FDG PET/CT和扩散权重MRI进行了分期.
外科手术包括下淋巴结解剖或哨兵淋巴结活检以确定最终的分期.

主要成果:

无论是PET/CT还是扩散权重MRI,都显示出高的初级病变检测率 (97.5%).
在两种方法中,状淋巴结转移检测的灵敏度为40.9%;PET/CT特异性为88.9%与MRI的83.3%相比.
较低的ADC值与雌激素和孕受体阳性状态相关. SUVmax和SUVmax比率与瘤大小和孕激素受体状态有显著的关联.

结论:

18F-FDG PET/CT和扩散权重MRI都非常有效地检测侵入性导管性乳腺癌.
与扩散权重MRI相比,PET/CT在识别状淋巴结转移方面具有更高的特异性.
像ADC和SUVmax这样的成像参数为瘤特征和患者子组提供了宝贵的见解.

关键词:

表面扩散系数扩散磁共振成像扩散乳腺癌是什么乳腺癌定子发射断层扫描 (PET) 是一种定子发射断层扫描.标准化最大吸收量标准化最大吸收量

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