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糖尿病视网膜病和心血管疾病:一篇文献综述

Wenhua Yu¹, Bo Yang¹, Siting Xu¹

¹Department of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang, People's Republic of China.

Diabetes, metabolic syndrome and obesity : targets and therapy

|January 2, 2024

概括

糖尿病视网膜病变 (DR) 显示出潜在的预测心血管疾病 (CVD) 由于共享的机制. 定量底部分析和细胞因子生物标志物为糖尿病患者的早期查和风险评估提供了新的途径.

科学领域:

内分泌学和新陈代谢学
眼科医生眼科眼科
心脏病学心脏病学

背景情况:

糖尿病并发症包括宏观 (例如,心血管疾病 - CVD) 和微血管 (例如,糖尿病视网膜病变 - DR) 问题.
心血管疾病是糖尿病患者死亡的主要原因,而心血管疾病对残疾有很大影响.
新出现的证据表明,连接DR和CVD的共同病理生理基础,暗示DR可能预测CVD风险.

研究的目的:

探索使用糖尿病视网膜病变 (DR) 作为心血管疾病 (CVD) 的预测因素的可行性.
审查DR和CVD背后的常见病理生理机制.
讨论DR诊断技术的进展,并确定用于早期DR查的生物标志物.

主要方法:

审查关于DR和CVD之间的病理生理联系的现有文献.
对DR的定量基金参数分析技术进步的分析.
对细胞因子和其他生物标志物的研究,以早期检测DR.

主要成果:

在DR中,定量基金参数被确定为心血管疾病的独立风险因素.
与DR相关的细胞因子显示了早期DR查的前景.
DR和CVD共享共同的潜在病理路径,支持DR的预测作用.

结论:

糖尿病视网膜病变 (DR) 具有很大的潜力作为心血管疾病 (CVD) 的预测标志物,这是由于共享的病理生理学.
定量基金分析和新型生物标志物为DR和CVD的早期检测和风险分层提供了有希望的策略.
对这些联系的进一步研究可以改善预防策略和糖尿病管理中的患者结果.

关键词:

生物标志物生物标志物心血管疾病心血管疾病糖尿病视网膜病变糖尿病视网膜病变光学连贯性断层扫描血管图谱病理生理机制的病理生理机制

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