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Updated: Sep 16, 2026

Isolation of Leukocytes from the Human Maternal-fetal Interface
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影响无细胞胎儿DNA (cffDNA) 分数的孕产妇和胎儿因素:系统性审查

Majid Zaki-Dizaji1, Arman Shafiee2, Omid Kohandel Gargari2

  • 1Human Genetics Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Journal of reproduction & infertility
|January 2, 2024
PubMed
概括

诸如母亲年龄,BMI和种族等因素可以影响非侵入性产前检测 (NIPT) 中的无细胞胎儿DNA (cffDNA) 水平. 了解这些影响对于准确的NIPT查结果至关重要.

关键词:
没有细胞的DNA.胎儿的分数 胎儿的分数怀孕年龄 怀孕年龄母亲的年龄 母亲的年龄非侵入性的产前检测.

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Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...