核心肌肉损伤中的异型骨化和富含血小板的血:一个机构经验超过6年
Alexander E Poor1,2,3, Adam C Zoga2, Alec Warren1
1Vincera Institute, Philadelphia, Pennsylvania, USA.
The American journal of sports medicine
|January 2, 2024
概括
治疗核心肌肉损伤的富血小板血 (PRP) 可能与运动员的异型骨化 (HO) 有关. 进一步的研究证实了这一关联,突出了PRP治疗运动相关的沟损伤的潜在风险.
科学领域:
- 整形外科手术 整形外科手术
- 运动医学 运动医学
- 再生医学是一种再生医学.
背景情况:
- 美国国家橄球联盟 (NFL) 球员的小腿损伤前一项关于富血小板血 (PRP) 的研究表明,与异型骨化 (HO) 有关.
- 这项研究提供了对2014年至2019年期间接受治疗的运动员中这种潜在关联的更广泛分析.
研究的目的:
- 评估先前接受PRP治疗失败的运动员的部手术后的短期临床结果.
- 测试假设,之前的PRP治疗与核心肌肉损伤 (CMIs) 患者的HO发展有关.
主要方法:
- 一项队列研究比较了接受PRP治疗的CMI运动员与没有接受PRP治疗的运动员.
- 通过临床检查,成像,手术内发现和病理确认来确定HO.
- 成功的手术被定义为恢复到受伤前的表现水平;PRP组被跟踪了≥2年.
主要成果:
- 在3642名CMI患者中,68人患有HO;其中44人先前接受过PRP治疗.
- 与匹配的对照组 (0%) 相比,接受PRP治疗的NFL球员的HO发病率显著更高 (78.6%).
- 手术后,PRP组的3个月成功率较低 (67.9%),而非PRP组 (96.4%),痕组织有助于延迟.
结论:
- 这项综合性研究支持了初步发现,PRP治疗CMI可能与HO相关.
- 结果表明,由于HO发展的风险,在某些与运动有关的伤害中使用PRP应谨慎使用.
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